TB500 10mg (Thymosin Beta-4)
High-Purity Peptide for Cellular Migration and Actin-Binding Research
$45.00$35.00
TB500, also known as Thymosin Beta-4, is a synthetic peptide fragment extensively studied in preclinical and in-vitro models. It is a naturally occurring peptide found in various tissues and is recognized for its vital role in cellular locomotion and cytoskeletal organization.
The 10mg formulation from Sigma Peptides is lab-tested to ensure 99%+ purity, providing a consistent model for analyzing peptide transport mechanisms and structural dynamics.
Core Research Highlights
In laboratory and in-vitro settings, TB500 10mg is utilized to explore:
Actin-Binding Potential: Researchers study its ability to bind G-actin and regulate polymerization processes, which are fundamental to cell shape and movement.
Cellular Migration Pathways: It is a primary tool for investigating how peptides modulate cellular locomotion and cytoskeletal dynamics.
Tissue Stress Modeling: Scientists use TB500 in simulated tissue models to assess structural peptide behavior under conditions of stress and repair.
Peptide Uptake & Bioavailability: It is frequently used in models evaluating how synthetic fragments are distributed and absorbed within various tissue types.
Technical Specifications
Feature | Specification |
Product Name | TB500 10mg |
Purity | ≥ 99% (Batch-tested and third-party verified) |
Form | Lyophilized (freeze-dried) white powder |
Sequence | Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser |
Molecular Formula | $C_{212}H_{350}N_{56}O_{78}S$ |
Molecular Weight | 4963.44 g/mol |
CAS Number | 77591-33-4 |
PubChem CID | 16132341 |
Preparation and Handling
TB500 is provided as a lyophilized powder in a sealed, sterile vial to ensure stability during transport and storage.
Reconstitution: This product requires Bacteriostatic Water for reconstitution prior to laboratory use.
Handling Protocol: Standard laboratory safety protocols should be followed. Researchers will need syringes, needles, and alcohol prep pads for proper extraction and application.
Note: The label quantity refers to the total amount of lyophilized peptide inside each vial.
Storage and Safety Guidelines
Strict storage conditions are required to maintain the chemical integrity of the peptide:
Lyophilized (Dry) Storage: Store in a cool, dry environment.
At 39°F (4°C): Stable for up to 2 years.
At -4°F (-20°C): Stable for up to 3 years.
Safety Warning: This product is RUO (Research Use Only) and is intended solely for in-vitro laboratory experiments. It is not approved for human or animal consumption, medical treatment, clinical trials, or as part of any human investigation.