PE-22-28 10mg (Grail Formula)

PE-22-28 is a synthetic research peptide belonging to the "Grail Formula" line, specifically studied for its neuro-regulatory and neuropeptide signaling properties. It is an analog of Spadin, a peptide derived from the propeptide of sortilin, and is primarily investigated for its interaction with TREK-1 (a two-pore domain potassium channel).

This product is independently verified to exceed 99% purity, ensuring the structural integrity and stability required for high-precision in-vitro research.

Core Research Highlights

In laboratory environments, PE-22-28 10mg is used to explore:

• Neurogenic Signaling: Researchers study the peptide's ability to influence neuro-regulatory pathways and evaluate its potential role in neurogenesis.

• TREK-1 Channel Modulation: A primary focus of research is its function as a TREK-1 channel antagonist, which is a mechanism often studied in the context of mood regulation models.

• Intracellular Communication: It is used as a model compound to analyze intracellular signaling patterns and receptor-associated biochemical responses.

• Structure-Function Behavior: The peptide's short, stable sequence allows for consistent evaluation of neuropeptide behavior in controlled laboratory conditions.

Technical Specifications

Preparation and Handling

PE-22-28 is provided as a lyophilized (freeze-dried) powder in a sealed vial to ensure maximum stability for in-vitro modeling.

• Reconstitution: For researchers within Europe, the product is supplied with bacteriostatic water. For orders outside the EU, only the peptide vial is included.

• Handling Protocol: Reconstitution should be performed carefully using sterile techniques to maintain the peptide's structural identity.

• Traceability: Each vial is part of the "Grail Formula" quality system, offering verified identity and batch-specific validation.

Storage and Safety Guidelines

To prevent chemical degradation and ensure analytical consistency:

• Storage (Lyophilized): Store in a cool, dry environment. Long-term storage at -20°C is recommended for maintaining stability for up to 2 years.

• Storage (Reconstituted): Once reconstituted, store at 2–8°C and use within a timeframe consistent with standard neuropeptide stability (typically 7–14 days).

• Safety Warning: This compound is strictly for laboratory research use only. It is not intended for human or veterinary consumption, medical treatment, or diagnostic use.