Melanotan I 10mg

Synthetic Peptide Analog for Pigmentation and Receptor Signaling Research

Melanotan I (Afamelanotide) is a synthetic peptide analog of the naturally occurring alpha-melanocyte-stimulating hormone (α-MSH). It is primarily studied for its high affinity and interaction with melanocortin receptors, specifically the MC1R subtype, which is the primary driver of pigment-related signaling and melanogenesis.

In laboratory environments, this peptide is a vital tool for exploring biochemical processes related to skin pigmentation, UV protection mechanisms, and intracellular signal transduction.

Core Research Highlights

Melanotan I is utilized in various preclinical and in vitro models to investigate:

• Melanocortin Receptor Binding: Researchers use it to analyze the binding characteristics and activation of the MC1R receptor in both cellular and animal models.

• Melanogenesis Mechanisms: It provides a controlled model for studying the pathway of melanin production and pigment biosynthesis.

• Signal Transduction: Investigations involving this peptide help map the intracellular signaling cascades triggered by α-MSH analogs.

• Comparative Specificity: It is often compared to other melanocortin analogs (such as Melanotan II) to evaluate differences in receptor specificity and efficacy.

Technical Specifications

Preparation and Handling

Melanotan I is supplied as a lyophilized (freeze-dried) powder in a sterile vial to ensure maximum stability during transit and storage.

• Reconstitution: Requires Bacteriostatic Water prior to use.

• Lab Protocol: The diluent should be introduced gently to prevent the mechanical degradation of the peptide.

• Research Supplies: Handling this compound requires standard laboratory equipment, including sterile syringes and alcohol pads for vial sanitization.

Storage and Safety Guidelines

To preserve the biological activity of the peptide, strict storage is required:

• Lyophilized (Dry) Storage: Store at 39°F (4°C) for up to 2 years, or -4°F (-20°C) for up to 3 years.

• Reconstituted (Liquid) Storage: Once dissolved, the solution must be kept refrigerated and used within a short research window to avoid degradation.

• Safety Warning: This product is intended for in-vitro laboratory research only. It is not approved for human consumption, therapeutic applications, or cosmetic procedures.