DSIP (Delta Sleep-Inducing Peptide) 5mg

Naturally Occurring Neuropeptide for Sleep & Stress Research

DSIP (Delta Sleep-Inducing Peptide) is a naturally occurring nonapeptide (nine amino acids) initially isolated from the central nervous system during electrically induced sleep in experimental models. While its name highlights its ability to induce delta (slow-wave) sleep, research suggests it plays a broader role in regulating various physiological and endocrine processes.

Core Benefits & Research Focus

DSIP is widely studied for its ability to modulate brain activity and maintain homeostasis during periods of stress:

• Sleep Cycle Regulation: Research in animal and human models suggests DSIP can reduce the time to fall asleep and significantly increase the duration of Slow-Wave Sleep (SWS), the deepest and most restorative stage of sleep. In one study, sleep increased by 59% within two hours of administration.

• Stress Modulatory Role: Investigated for its ability to lower corticosterone levels (a key stress marker) and stabilize the opioidergic system. It may act as a buffer against emotional and physiological stress by dampening stimulatory NMDA receptors and amplifying calming GABA signals.

• Endocrine Support: Studies indicate DSIP may stimulate the release of Growth Hormone (GH) and Luteinizing Hormone (LH) by acting on the hypothalamus and pituitary glands.

• Longevity & Antioxidant Properties: In murine models, DSIP has been linked to a 24% increase in lifespan and a 2.5-fold decrease in the occurrence of malignancies. It is hypothesized to stimulate the body's endogenous antioxidant systems (such as superoxide dismutase and catalase) to combat oxidative stress.

• Withdrawal & Pain Management: Early clinical research suggested potential for DSIP in mitigating pain and alleviating withdrawal symptoms, possibly through its indirect interaction with opioid receptors.

Technical Specifications

Safety & Storage

• Usage Disclaimer: This product is sold for research and laboratory purposes only and is not for human consumption.

• Interactions: In research, its GH-releasing effects were blocked by pimozide (a dopamine antagonist), suggesting a complex dopaminergic mechanism of action.

• Storage: Store the lyophilized powder in a cool, dry place. For long-term stability, keep at -20°C. Once reconstituted with bacteriostatic water, keep refrigerated and use within a short timeframe to prevent degradation.