AOD 9604 (5mg)

Targeted Lipolytic Fragment for Obesity Research

AOD 9604 (Advanced Obesity Drug) is a synthetic analog of human growth hormone (hGH), specifically a modified version of the C-terminal fragment (amino acids 176–191). It was developed to isolate the fat-burning properties of growth hormone while avoiding its potentially unwanted effects, such as increased insulin resistance or excessive bone/organ growth.

Core Benefits & Research Focus

AOD 9604 is primarily investigated for its unique ability to regulate fat metabolism without stimulating the production of IGF-1:

• Lipolysis & Fat Oxidation: Research suggests the peptide mimics the way natural growth hormone regulates fat metabolism but with greater potency. It stimulates lipolysis (the breakdown of stored fats) and inhibits lipogenesis (the transformation of non-fatty foods into body fat).

• Weight Management Studies: In animal models, chronic treatment with AOD 9604 led to significant weight loss and a reduction in excess body fat. Clinical trials with obese human subjects have also observed consistent weight loss and improvements in cholesterol profiles.

• Tissue Repair & Cartilage Regeneration: Studies on rabbit models suggest that AOD 9604, especially when combined with hyaluronic acid, may enhance cartilage regeneration and repair. It is hypothesized to promote the differentiation of stem cells into bone and muscle cells.

• Cancer Research Support: Emerging research has explored using AOD 9604 as a carrier to enhance the targeted delivery and toxicity of chemotherapeutic agents, such as doxorubicin, against breast cancer cells.

Technical Specifications

Suggested Usage & Protocols (For Research Purposes)

• Administration: In research settings, AOD 9604 is often studied via subcutaneous injection, typically administered in the morning on an empty stomach to maximize lipolytic activity.

• Reconstitution: The lyophilized powder must be reconstituted with bacteriostatic water or a sterile aqueous buffer before use.

• Observed Effects: Weight loss in studies often remains consistent throughout the treatment period without significant metabolic plateauing.

Safety & Storage

• Usage Disclaimer: This product is sold for research and laboratory purposes only and is not for human consumption.

• Metabolic Safety: Unlike full-length growth hormone, AOD 9604 has not been observed to disrupt insulin sensitivity or increase glucose tolerance issues in research subjects.

• Storage: Store the lyophilized powder at -20°C for long-term stability. Once reconstituted, the solution should be kept refrigerated and used within a short timeframe to prevent degradation.